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A Reference Ontology for Bioinformatics: The Foundational Model of Anatomy

Rosse, Cornelius and Mejino, Jose L V (2003) A Reference Ontology for Bioinformatics: The Foundational Model of Anatomy. Journal of Biomedical Informatics 36:pp. 478-500.

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The Foundational Model of Anatomy (FMA), initially developed as an enhancement of the anatomical content of UMLS, is a domain ontology of the concepts and relationships that pertain to the structural organization of the human body. It encompasses the material objects from the molecular to the macroscopic levels that constitute the body and associates with them nonmaterial entities (spaces, surfaces, lines and points) required for describing structural relationships. The disciplined modeling approach employed for the development of the FMA relies on a set of declared principles, high level schemes, Aristotelian definitions and a frame-based authoring environment. We propose the FMA as a reference ontology in biomedical informatics for correlating different views of anatomy, aligning existing and emerging ontologies in bioinformatics and providing a structure-based template for representing biological functions.

Item Type:Journal (Paginated)
Keywords:ontology, knowledge representation, anatomy, mereotopology, embryology, developmental biology
Projects:Foundational Model of Anatomy
Subjects:SIG Publications
ID Code:135
Deposited By:Hinshaw, Kevin
Deposited On:04 August 2003