Composite annotations: requirements for mapping multiscale data and models to biomedical ontologies

Cook, Daniel L and Mejino, Jose L V and Neal, Maxwell L and Gennari, John H (2009) Composite annotations: requirements for mapping multiscale data and models to biomedical ontologies. In Proceedings, Engineering in Medicine and Biology Conference, Montreal.

Abstract

Abstract—Current methods for annotating biomedical data resources rely on simple mappings between data elements and the contents of a variety of biomedical ontologies and controlled vocabularies. Here we point out that such simple mappings are inadequate for large-scale multiscale, multidomain integrative “virtual human” projects. For such integrative challenges, we describe a “composite annotation” schema that is simple yet sufficiently extensible for mapping the biomedical content of a variety of data sources and biosimulation models to available biomedical ontologies.